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Anti- CALB2 Antibody EPR1799(2)
Also for CALB2 (NM_001740)
|A synthetic peptide corresponding to residues in human Calretinin was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens calbindin 2 (CALB2), transcript variant CALB2|
|CAB29; CAL2; CR|
|Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to the calbindin family. It is mainly found in neuronal tissue, highly expressed in auditory neurons. It has been implicated as a calcium buffer, calcium sensor, and regulator of apoptosis (1). Calretinin is considered a specific marker of mesothelial cells; it is the only marker that has can distinguish between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas (2). It is widely used in a panel of markers for distinguishing mesothelioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin, CEA, and cytokeratin 5/6 (3).|
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Western blot - Anti-Calretinin antibody [EPR1799(2)]; All lanes : Anti-Calretinin antibody [EPR1799(2)] at 1/1000 dilution.Lane 1 : Fetal brain lysates.Lane 2 : SH-SY5Y lysates.Lane 3 : 293T lysates.Lane 4 : Fetal kidney lysates.Lane 5 : U87-MG lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 31 kDa.