Homo sapiens dickkopf 1 homolog (Xenopus laevis) (DKK1)
Synonyms:
DKK-1; SK
Immunogen
A synthetic peptide corresponding to residues in human DKK1 was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood are associated with the presence of osteolytic bone lesions in patients with multiple myeloma (1).
Related Pathway
Wnt Signaling Pathway
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