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Anti-DAPK2 Antibody EPR1634(2)
Also for DAPK2 (NM_014326)
|A synthetic peptide corresponding to residues on the C-terminus in human DAPK2 was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens death-associated protein kinase 2 (DAPK2)|
|Protein kinase termed death-associated protein kinase 2 (DAPK2) dependent on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. The region of homology spans the catalytic domain and the CaM-regulatory region, whereas the remaining C-terminal part of the protein differs completely from DAP kinase and displays no homology to any known protein. The catalytic domain is also homologous to the recently identified ZIP kinase and to a lesser extent to the catalytic domains of DRAK1 and -2 (1). Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling (2).|
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Western blot - DAP Kinase 2 antibody [EPR1634(2)]; All lanes : Anti-DAP Kinase 2 antibody [EPR1634(2)] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : HepG2 cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 43 kDa.