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Anti-WFDC2 Antibody EPR4743
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Also for WFDC2 (NM_006103)
|A synthetic peptide corresponding to residues in human HE4 was used as an immunogen.|
||FC: 1:100 - 500, ICC: 1:100 - 250, WB: 1:1,000 - 10,000,
|Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens WAP four-disulfide core domain 2 (WFDC2)|
|dJ461P17.6; EDDM4; HE4; WAP5|
|HE4, or WAP four-disulfide core domain 2, is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and it functions as a protease inhibitor in many family members. HE4 is expressed in pulmonary epithelial cells, and it is also found to be expressed in some ovarian cancers. HE4 is a small secretory protein, which may be involved in sperm maturation.|
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Western blot analysis on (A) HT-29, (B) SW480, (C) ovary cancer, and (D) SK-OV-3 lysates using anti-HE4 RabMAb .
Flow cytometric analysis of permeabilized SW480 cells using anti-HE4 RabMAb (red) or a rabbit IgG (negative) (green).