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Home Antibody All anti-ACADM antibodies

Anti-ACADM Antibody EPR3708

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307768
  • Rabbit monoclonal antibody against ACADM(clone EPR3708)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400001) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for ACADM (NM_000016)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ACADM was used as an immunogen.
Clone NameEPR3708 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:10 - 100, WB: 1:10,000-50,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM), transcript variant 1
Alternative NameACAD1; MCAD; MCADH
Database LinkNP_000007
FunctionMedium-chain specific acyl-CoA dehydrogenase (ACADM) is a homotetramer enzyme of the mitochondrial flavoenzyme family that catalyzes the initial reaction in medium chain fatty acid beta-oxidation (1, 2). ACADM is specific for acyl chain lengths of 4 to 16 (3). It utilizes the electron transfer flavoprotein (ETF) as an electron acceptor that transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (3). Defects in the ACADM gene cause medium-chain acyl-CoA dehydrogenase deficiency (MCADD), a metabolic disorder characterized by fasting hypoglycemia (3). Mutation analysis can diagnose MCADD, which is currently screened in newborns, since its monogene may be modified by genetic variations (4).
Related Pathway

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WB Image
Western blot - ACADM antibody [EPR3708]; All lanes : Anti-ACADM antibody [EPR3708] at 1/10000 dilution.Lane 1 : Human heart lysate.Lane 2 : fetal liver lysate.Lane 3 : HeLa cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP conjugated Goat anti-Rabbit Ig at 1/2000 dilution.Predicted band size : 47 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ACADM antibody [EPR3708]; TA307768, at 1/100 dilution, staining ACADM in formalin-fixed, paraffin-embedded Human liver tissue by immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - ACADM antibody [EPR3708]; Immunofluorescent staining of ACADM in HeLa cells using TA307768 at 1/100 dilution.

 

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