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Home Antibody All anti-ALDOB antibodies

Anti-ALDOB Antibody EPR3137

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307760
  • Rabbit monoclonal antibody against Aldolase B (clone EPR3137 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400007) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(5)
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Also for ALDOB (NM_000035)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Aldolase B was used as an immunogen.
Clone NameEPR3137 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsIHC-P: 1:100 - 1:250; WB: 1:1000 - 1:2000
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IP.

Reference Data

Target NameHomo sapiens aldolase B, fructose-bisphosphate (ALDOB)
Alternative NameALDB; ALDO2
Database LinkNP_000026
FunctionAldolase B is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. Aldolase B catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is involved in both glycolytic and gluconeogenic pathways, where its quaternary structure is critical for maintaining its full catalytic function. Hereditary fructose intolerance (HFI), a potentially fatal human autosomal recessive disease of carbohydrate metabolism, results with Aldolase B deficiency. Partially active Aldolase B, however, has been reported in an HFI individuals, which supports the hypothesis that adequate gluconeogenesis/glycolysis is maintained in HFI patients by the presence of partially active enzymes (1-4).
Related Pathway

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WB Image
Western blot - Anti-ALDOB antibody [EPR3137]; All lanes : Anti-ALDOB antibody [EPR3137] at 1/1000 dilution.Lane 1 : Human fetal liver cell lysate.Lane 2 : Human fetal kidney cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 39 kDa.Observed band size : 40 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALDOB antibody [EPR3137]; Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human fetal liver tissue staining ALDOB with TA307760 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ALDOB antibody [EPR3137]; Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human adult liver tissue staining ALDOB with TA307760 at 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3137](TA307760); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA307760 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3137](TA307760); Immunohistochemical analysis of paraffin embedded normal Human breast tissue using TA307760 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-ALDOB antibody [EPR3137](TA307760); Immunohistochemical analysis of paraffin embedded normal Human kidney tissue using TA307760 showing +ve staining.

 

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