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Anti-KRT18 Antibody EPR1625
Also for KRT18 (NM_000224)
|A synthetic peptide corresponding to residues in N-terminus of human Cytokeratin 18 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; ICC/IF: 1:500 - 1:1000
|Preservative: 0.01% Sodium azide|
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens keratin 18 (KRT18), transcript variant 1|
|Keratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (1-3). Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells, forming alpha-helical coiled-coil dimers which associate laterally and end-to-end to form 10-nm diameter filaments (4).|
EGFR1 Signaling Pathway
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Western blot - Anti-Cytokeratin 18 antibody [EPR1625]; All lanes : Anti-Cytokeratin 18 antibody [EPR1625] at 1/10000 dilution.Lane 1 : HeLa cell lysates .Lane 2 : MCF-7 cell lysates .Predicted band size : 48 kDa.
Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 18 antibody [EPR1625]; Immunofluorescent staining of HeLa cells labelling Cytokeratin 18 using TA307740, at 1/500 dilution.