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Anti-VDR Antibody EPR4552
|A synthetic peptide corresponding to residues in human Vitamin D3 Receptor was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), transcript variant 1|
|Vitamin D3 Receptor is the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. It belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism, though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in Vitamin D3 Receptor are associated with type II vitamin D-resistant rickets.|
TGF Beta Signaling Pathway
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Western blot - Vitamin D Receptor antibody [EPR4552]; All lanes : Anti-Vitamin D Receptor antibody [EPR4552] at 1/1000 dilution.Lane 1 : T47D cell lysate.Lane 2 : SKBR-3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 48 kDa.Observed band size : 48 kDa.