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Anti-IL2 Antibody EPR2780
|A synthetic peptide corresponding to residues in human IL-2 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens interleukin 2 (IL2)|
|IL-2; lymphokine; TCGF|
|Interleukin-2 (IL-2) is an immunoregulatory cytokine that functions as a growth factor and central regulator in the immune system (1, 2). It participates in modulating the immune response by helping control the rate of clonal expansion of lymphocytes (3). IL-2 acts through a quaternary receptor signaling complex containing alpha, beta, and common gamma chain receptors (1). IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial for regulation of the immune response. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (4). |
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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Western blot - IL2 antibody [EPR2780]; All lanes : Anti-IL2 antibody [EPR2780] at 1/1000 dilution.Lane 1 : Human thymus lysate.Lane 2 : PBMC lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IL2 antibody [EPR2780]; ab92381 at 1/250 dilution staining IL2 in Formalin-fixed, Paraffin-embedded Human tonsil tissue. Detection: DAB staining.