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Home Antibody All anti-CGA antibodies

Anti-CGA Antibody EP3373

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SKU Description Amount Price Availability*  
TA307674 Rabbit monoclonal antibody against CGA (clone EP3373 ) 100ul $325 In Stock
LC400243 CGA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(6)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C terminus of human CGA was used as an immunogen.
Clone NameEP3373 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1:100 - 250, WB: 1:500 - 1,000,
Predicted MW Explanation 13 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens glycoprotein hormones, alpha polypeptide (CGA), transcript variant 2
Alternative NameCG-ALPHA; FSHA; GPHa; GPHA1; HCG; LHA; TSHA
Database LinkNP_000726
Entrez Gene 1081 Human
FunctionCGA belongs to the glycoprotein hormone alpha chain family that includes the alpha subunit of chronic gonadotropin (CG), lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH). The glycoprotein hormones have the most complex chemical structures of the classical protein hormones. They are dimmers consisting of alpha and beta subunits that are associated noncovalently (1, 4). The alpha subunit is common to all of the hormones; however, their beta chains are unique and confer biological specificity (1). These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function (2). The hormones LH, FSH and TSH are secreted by the anterior pituitary gland, while CG is secreted by the placenta (3).
Related PathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome Neuroactive ligand-receptor interactionGnRH signaling pathwayAutoimmune thyroid disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Glycoprotein hormones (alpha 5) antibody [EP3373]; All lanes : Anti-Glycoprotein hormones (alpha 5) antibody [EP3373] at 1/500 dilution.Lane 1 : JAR cell lysates, treated with Hydroxyurea.Lane 2 : JAR cell lysates, untreated .Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 13 kDa.Observed band size : 18 kDa .
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glycoprotein hormones (alpha 5) antibody [EP3373]; TA307674 at 1/100 dilution staining Glycoprotein hormones (alpha 5) in Human placenta by Immunohistochemistry, Paraffin-embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Glycoprotein hormones (alpha 5) antibody [EP3373](TA307674); TA307674 showing negative staining in Normal brain tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Glycoprotein hormones (alpha 5) antibody [EP3373](TA307674); TA307674 showing negative staining in Normal breast tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Glycoprotein hormones (alpha 5) antibody [EP3373](TA307674); TA307674 showing negative staining in Normal tonsil tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Glycoprotein hormones (alpha 5) antibody [EP3373](TA307674); TA307674 showing negative staining in Normal kidney tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Glycoprotein hormones (alpha 5) antibody [EP3373](TA307674); TA307674 showing negative staining in Normal liver tissue.
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