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Anti-AKT1 Phospho Antibody EPR4157
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for AKT1 (NM_001014431)
|A phospho specific peptide corresponding to residues surrounding threonine 450 of human Akt1 was used as an immunogen. This antibody only detects Akt1 phosphorylated at threonine 450.|
|Human, Mouse, Rat
||IHC: 1:50 - 100, IP: 1:10 - 100, WB: 1:1,000 -10,000,
|Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens v-akt murine thymoma viral oncogene homolog 1 (AKT1), transcript variant 3|
|AKT; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA|
|Akt1/PKBa is a Serine/Threonine protein kinase whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, and cell growth. Akt1/PKBa is activated by various growth and survival factors (1). Akt1/PKBa inhibits apoptosis by phosphorylating and inactivating several targets, including caspase-9 (2). Akt1/PKBa regulates glycogen synthesis by phosphorylating and inactivating glycogen synthase kinase-3a and b (3,4).|
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
Signaling by GPCR
Toll-like receptor signaling pathway
Wnt Signaling Pathway
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Western blot analysis on NIH/3T3 cell lysate using anti-Akt1 Phospho (pT450) RabMAb .
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-Akt1 Phospho (pT450) RabMAb .