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Home Antibody All anti-FANCD2 antibodies

Anti-FANCD2 Antibody EPR2302

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307630
  • Rabbit monoclonal antibody against FANCD2(clone EPR2302)
100ul 325
$292
In Stock
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WB(1)
IHC(1)
IF(1)
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Also for FANCD2 (NM_001018115)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FANCD2 was used as an immunogen.
Clone NameEPR2302 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 2
Alternative NameFA-D2; FA4; FACD; FAD; FAD2; FANCD
Database LinkNP_001018125
FunctionThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group, FANCH, is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. FANCD2 is also known as Fanconi anemia group D2 protein. It is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair.
Related Pathway

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WB Image
Western blot - FANCD2 antibody [EPR2302]; All lanes : Anti-FANCD2 antibody [EPR2302] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : SKBR-3 cell lysate.Lane 4 : K562 cell lysate.Lane 5 : HL60 cell lysate.Lane 6 : C6 cell lysate.Lane 7 : PC-12 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 166 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FANCD2 antibody [EPR2302]; Immunohistochemical staining of paraffin-embedded Human tonsil tissue using TA307630 at a dilution of 1/100.
IF Image
Immunocytochemistry/ Immunofluorescence - FANCD2 antibody [EPR2302]; Immunofluorescent staining of HeLa cells using TA307630 at a dilution of 1/250.

 

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