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Home Antibody All anti-RGS9 antibodies

Anti-RGS9 Antibody EPR2873

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307611
  • Rabbit monoclonal antibody against PGS9(clone EPR2873)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421179) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
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Also for RGS9 (NM_001081955)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human RGS9 was used as an immunogen
Clone NameEPR2873 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000; IP: 1:10; ICC: 1:50 - 1:100; FC: 1:30
Predicted MW Explanation 77 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 9 (RGS9), transcript variant 2
Alternative NamePERRS; RGS9L
Database LinkNP_001075424
Entrez Gene 8787 Human
Entrez Gene 19739 Mouse
Entrez Gene 29481 Rat
FunctionRegulator of G-protein signaling 9 (RGS9) is a GTPase-activating protein. It enhances the time resolution of G protein signaling cascades by accelerating GTP hydrolysis of G alpha subunits of heterotrimeric G proteins (1, 2). RGS9 deactivates the G proteins (transducins) in the rod and cone phototransduction cascades. It is anchored to photoreceptor membranes by the transmembrane protein R9AP (RGS9 anchor protein), which enhances RGS9 activity up to 70-fold (3). As a peripheral membrane protein, RGS9 is highly expressed in the caudate and putamen and lower levels are found in the hypothalamus, nucleus accumbens and cerebellum. Defects in RGS9 are suggested as the cause of prolonged electroretinal response suppression, also known as bradyopsia (4).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - RGS9 antibody [EPR2873]; All lanes : Anti-RGS9 antibody [EPR2873] at 1/1000 dilution.Lane 1 : PC12 lysates.Lane 2 : Human spleen lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 77 kDa.Observed band size : 55 kDa .
FC Image
Flow Cytometry - RGS9 antibody [EPR2873]; Flow cytometric analysis of RGS9 in permeabilized PC12 cells, using TA307611 (red) at a 1/30 dilution or a rabbit IgG (negative) (green).

 

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