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Anti-CTNND1 Antibody EPR357(2)
Also for CTNND1 (NM_001085458)
|A synthetic peptide corresponding to residues in human p120 Catenin was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC, IF
||ICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:10 - 100, WB: 1:1,000 - 10,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 1|
|CAS; CTNND; p120; p120(CAS); p120(CTN); P120CAS; P120CTN|
Entrez Gene 1500 Human
Entrez Gene 12388 Mouse
Entrez Gene 311163 Rat
|Catenins are proteins that are linked to the cytoplasmic domain of transmembrane cadherins. p120 Catenin is one member of this Armadillo gene family of junctional plaque proteins (1-3). The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Recently it became clear that some catenins also mediate nuclear signaling (1). p120 Catenin is implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.|
|Druggable Genome Adherens junctionLeukocyte transendothelial migration|
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Western blot - delta 1 Catenin antibody [EPR357(2)]; All lanes : Anti-delta 1 Catenin antibody [EPR357(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 108 kDa.
Other-Anti-delta 1 Catenin antibody [EPR357(2)](TA307610); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - delta 1 Catenin antibody [EPR357(2)]; Paraffin embedded Human breast carcinoma tissue (1) and Human colonic adenocarcinoma tissue (2) labelled with at 1/100 dilution.
Immunocytochemistry/ Immunofluorescence - delta 1 Catenin antibody [EPR357(2)]; Immunofluorescence of A431 cells labelled with TA307610 at 1/100 dilution.