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Home Antibody All anti-FDPS antibodies

Anti-FDPS Antibody EPR4628

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307581
  • Rabbit monoclonal antibody against FDPS(clone EPR4628)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427716) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for FDPS (NM_001135821)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human FDPS was used as an immunogen.
Clone NameEPR4628 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens farnesyl diphosphate synthase (FDPS), transcript variant 2
Alternative NameFPPS; FPS
Database LinkNP_001129293
Entrez Gene 2224 Human
FunctionFDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption (1).
Related PathwayDruggable Genome Terpenoid backbone biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - FDPS antibody [EPR4628]; All lanes : Anti-FDPS antibody [EPR4628] at 1/1000 dilution.Lane 1 : THP1 cell lysates.Lane 2 : HepG2 cell lysates.Lane 3 : Human fetal liver lysates.Predicted band size : 48 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FDPS antibody [EPR4628]; TA307581 at 1/100 dilution staining FDPS in Human kidney by Immunohistochemistry, Paraffin-embedded tissue.

 

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