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Home All anti-KRT13 antibodies

Anti-KRT13 Antibody EPR3672

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA307576
  • Rabbit monoclonal antibody against Cytokeratin 13 (clone EPR3672 )
100ul $325 3-7 Days Add to Shopping Cart
IHC(1)
Gene NameHomo sapiens keratin 13 (KRT13), transcript variant 2
Synonyms:CK13; K13
ImmunogenA synthetic peptide corresponding to residues in human CK13 was used as an immunogen.
BufferStore at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Clone NameEPR3672 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *IHC Suggested DilutionsICC: 1:50 - 100, IHC: 1:100 - 250, WB: 1:2,000 - 10,000,
BackgroundKeratins are a family of highly homologous proteins expressed as pairs of acidic and basic forms which make intermediate filaments in epithelial cells. Keratin 13 (CK13) is the major acidic keratin, which together with K4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia (1). White sponge nevus (WSN) is a rare autosomal dominant disorder of non-cornifying squamous epithelial differentiation that presents clinically as bilateral white, soft, thick plaques of the oral mucosa. In WSN, the restriction of lesions to mucosal epithelia and the suprabasal cell histopathology parallels the tissue-specific expression of keratins 4 and 13 in the differentiating cell layers (2).
Related Pathway

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IHC Image
B. Immunohistochemical analysis of paraffin-embedded human transitional cell carcinoma of urinary bladder using anti-CK13 RabMAB.

 

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