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Home Antibody All anti-ESR2 antibodies

Anti-ESR2 Antibody EPR3777

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307543
  • Rabbit monoclonal antibody against ER beta(clone EPR3777)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400556) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for ESR2 (NM_001437)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to N-terminus of human ER beta was used as an immunogen.
Clone NameEPR3777 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsICC: 1:100 - 250, IP: 1:10 - 100, WB: 1:1000 - 10,000,
Predicted MW Explanation 59 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant a
Alternative NameER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2
Database LinkNP_001428
Entrez Gene 2100 Human
FunctionEstrogen Receptor beta (ER beta) is a nuclear hormone receptor which is highly homologous to ER alpha. It functions as a ligand-activated transcription factor, binding to estrogens and activation expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (1). Studies have shown ER beta play a role in modulation of the effects of ER alpha, possibly by inhibiting the transcription activation of ER alpha (2). ER beta is expressed in many tissues, including human thymus, spleen, ovary and testis. It is also highly expressed in endothelial and vascular smooth muscles cells, and the expression of ER beta in these areas has a positive correlation with increased coronary artery plaque (3).
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Estrogen Receptor beta antibody [EPR3777]; All lanes : Anti-Estrogen Receptor beta antibody [EPR3777] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit antibody at 1/2000 dilution.Predicted band size : 59 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Estrogen Receptor beta antibody [EPR3777]; TA307543 at 1/100 dilution staining Estrogen Receptor beta in HeLa cells by immunofluorescence.

 

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