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Home All anti-CD79A antibodies
Anti-CD79A Antibody EP3618
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for CD79A (NM_001783)
OriGene Data
| A synthetic peptide derived from the extracellular region of human CD79a protein. |
| EP3618 |
Rabbit IgG |
| Human |
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| WB, IHC |
FC: 1:140, IHC: 1:100 - 250, WB: 1:5000 - 20,000, |
| Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens CD79a molecule, immunoglobulin-associated alpha (CD79A), transcript variant 1 |
| IGA; MB-1 |
| NP_001774 |
| CD79a (mb-1/ B lymphocyte-specific MB-1 protein) was originally identified on the basis of its restricted expression in lymphocytes of B lineage (1). CD79a associates with surface IgM-receptors; it has been implicated in the signal transduction pathways and in the regulation of type of type 2A-related serine/threonine phosphatases catalytic activity (2). A disulphide-linked heterodimer, consisting of CD79a (mb-1) and CD79b / B29 polypeptides, non-covalently associates with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79 is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also CD79 interacts with and increases activity of some Src-family tyrosine kinases. (3). |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
A. Western blot analysis on (A) Raji, (B) Daudi cell lysates and (C) Hu-tonsil and (D) Hu-spleen tissue lysate using anti-CD79 RabMAb .
IHC Image
B. Immunohistochemical analysis of paraffin-embedded human tonsils tissue using anti-CD79 RabMAb .
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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