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Home Antibody All anti-CD97 antibodies

Anti-CD97 Antibody EPR4427

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SKU Description Amount Price Availability*  
TA307505
  • Rabbit monoclonal antibody against CD97(clone EPR4427)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400675) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(3)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human CD97 was used as an immunogen.
Clone NameEPR4427 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens adhesion G protein-coupled receptor E5 (ADGRE5), transcript variant 2
Alternative NameCD97; TM7LN1
Database LinkNP_001775
Entrez Gene 976 Human
Entrez Gene 26364 Mouse
FunctionCD97 is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules. It is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. CD97 has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation.
Related PathwayGPCRSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - CD97 antibody [EPR4427]; All lanes : Anti-CD97 antibody [EPR4427] at 1/1000 dilution.Lane 1 : Human tonsil lysate.Lane 2 : Jurkat cell lysate.Lane 3 : U937 cell lysate.Lane 4 : Human fetal thymus lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 92 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human spleen by Immunohistochemistry, Paraffin-embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human colonic adenocarcinoma by Immunohistochemistry, Paraffin-embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human colonic tonsil by Immunohistochemistry, Paraffin-embedded tissue.
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