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 Home All anti-CDH4 antibodies

Anti-CDH4 Antibody EPR4836

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SKU Description Amount Price Availability*  
TA307504
  • Rabbit monoclonal antibody against R-Cadherin(clone EPR4836)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400684) , 20ug
 100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human R-Cadherin was used as an immunogen.
Clone NameEPR4836 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsIP: 1:10 - 100, WB: 1:10,000 - 50,000,
BufferStore at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens cadherin 4, type 1, R-cadherin (retinal) (CDH4), transcript variant 1
Alternative NameCAD4; RCAD
Database LinkNP_001785
FunctionR-Cadherin is a classical cadherin from the cadherin superfamily. This protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization (1).
Related Pathway

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WB Image
Western blot analysis on (A) HepG2, (B) fetal brain, and (C) SH-SY5Y cell lysates using anti-R-Cadherin RabMAb .

 

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