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Home Antibody All anti-CDH4 antibodies

Anti-CDH4 Antibody EPR4836

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307504
  • Rabbit monoclonal antibody against R-Cadherin(clone EPR4836)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400684) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human R-Cadherin was used as an immunogen.
Clone NameEPR4836 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 100 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens cadherin 4, type 1, R-cadherin (retinal) (CDH4), transcript variant 1
Alternative NameCAD4; R-CAD; RCAD
Database LinkNP_001785
Entrez Gene 1002 Human
Entrez Gene 12561 Mouse
Entrez Gene 114588 Rat
FunctionR-Cadherin is a classical cadherin from the cadherin superfamily. This protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization (1).
Related PathwayTransmembrane Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - R Cadherin antibody [EPR483]; All lanes : Anti-R Cadherin antibody [EPR4836] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Fetal brain lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug/ml per lane.Predicted band size : 100 kDa.

 

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