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Anti-CDH4 Antibody EPR4836
Also for CDH4 (NM_001794)
|A synthetic peptide corresponding to residues in human R-Cadherin was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens cadherin 4, type 1, R-cadherin (retinal) (CDH4), transcript variant 1|
|R-Cadherin is a classical cadherin from the cadherin superfamily. This protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization (1).|
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Western blot - R Cadherin antibody [EPR483]; All lanes : Anti-R Cadherin antibody [EPR4836] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Fetal brain lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg/ml per lane.Predicted band size : 100 kDa.