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Home Antibody All anti-FNTB antibodies

Anti-FNTB Antibody EPR4706

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307492
  • Rabbit monoclonal antibody against FNTB(clone EPR4706)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400742) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for FNTB (NM_002028)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human FNTB was used as an immunogen.
Clone NameEPR4706 IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:50 - 1:100
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens farnesyltransferase, CAAX box, beta (FNTB)
Alternative NameFPTB
Database LinkNP_002019
FunctionThe mammalian enzyme protein farnesyltransferase is a heterodimeric protein composing of two nonidentical subunits designated alpha and beta, which catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins (1,2). The beta subunit is responsible for peptide-binding (1). Chemical modification and site-directed mutagenesis studies have identified a conserved cysteine residue of protein farnesyltransferase, Cys299, in the beta subunit, as important for catalytic activity and zinc binding, suggesting that the thiolate of this residue may directly coordinate the zinc ion (3).
Related Pathway

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WB Image
Western blot - FNTB antibody [EPR4706]; All lanes : Anti-FNTB antibody [EPR4706] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : K562 cell lysate.Lane 4 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 49 kDa.

 

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