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Home Antibody All anti-GCG antibodies

Anti-GCG Antibody EP3070

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307485
  • Rabbit monoclonal antibody against Glucagon(clone EP3070)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419562) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for GCG (NM_002054)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Glucagon was used as an immunogen.
Clone NameEP3070 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:1000 - 1:5000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens glucagon (GCG)
Alternative NameGLP1; GLP2; GRPP
Database LinkNP_002045
FunctionGlucagon is an important hormone involved in glucose metabolism and homeostasis (1). It regulates blood glucose by increasing gluconegenesis and decreasing glycolysis. It is synthesized and released by the alpha-cells of the islets of Langerhans in pancreas as the proglucagon and is preteolytically processed to yield the mature peptide (2). When the glucose level in the blood is low (hypoglycemia), Glucagon is released and binds to glucagon receptors on hepatocytes, causing the liver to release glucose through glycogenolysis. Upon the depletion of stored glycogen in the liver, Glucagon then stimulates liver to synthesize additional glucose by gluconeogenesis. It is a counter regulatory hormone of insulin, and plays an important role in initiating and maintaining hyperglycemic conditions in diabetes (3).
Related Pathway
Signaling by GPCR

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Glucagon antibody [EP3070]; All lanes : Anti-Glucagon antibody [EP3070].Lane 1 : HepG2 Lysate.Lane 2 : Human Fetal liver lysate.Lane 3 : Mouse kidney lysate.Lane 4 : Mouse spleen Lysate.Predicted band size : 21 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glucagon antibody [EP3070]; TA307485, at 1/1000 dilution, staining Glucagon in paraffin embedded Human pancreas tissue by Immunohistochemistry.

 

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