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Home Antibody All anti-ITGAE antibodies

Anti-ITGAE Antibody EPR4166

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307464
  • Rabbit monoclonal antibody against CD103 / Integrin alpha-E(clone EPR4166)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419469) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for ITGAE (NM_002208)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to the extracellular domain and light chain region of human CD103 / Integrin alpha-E was used as an immunogen.
Clone NameEPR4166 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) (ITGAE)
Alternative NameCD103; HUMINAE
Database LinkNP_002199
FunctionIntegrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD103 / Integrin alpha-E is an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 / Integrin alpha-E is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL); in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Related Pathway
Focal Adhesion

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Integrin alpha E antibody [EPR4166]; All lanes : Anti-Integrin alpha E antibody [EPR4166] at 1/1000 dilution.Lane 1 : HuT-78 cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : A431 cell lysate.Lane 4 : HeLa cell lysate.Lane 5 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 130 kDa.Observed band size : 150 kDa .

 

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