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Anti-LCP1 Antibody EPR4278
Also for LCP1 (NM_002298)
|A synthetic peptide corresponding to residues in human Plastin L was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000; FC: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens lymphocyte cytosolic protein 1 (L-plastin) (LCP1)|
|CP64; L-PLASTIN; LC64P; LPL; PLS2|
|Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform that is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hematopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hematopoietic origin, suggesting that its expression is induced accompanying tumorigenesis in solid tissues.|
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Western blot - Plastin L antibody [EPR4278]; All lanes : Anti-Plastin L antibody [EPR4278] at 1/10000 dilution.Lane 1 : THP-1 cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 70 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Plastin L antibody [EPR4278]; Immunohistochemical staining of paraffin-embedded Human tonsil tissue using TA307457 at a dilution of 1/250.