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Home Antibody All anti-KRT13 antibodies

Anti-KRT13 Antibody EPR3671

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307432
  • Rabbit monoclonal antibody against Cytokeratin 13 (clone EPR3671 )
100ul $325 In Stock

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WB(1)
IHC(6)
Assay(1)
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Also for KRT13 (NM_002274)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CK13 was used as an immunogen.
Clone NameEPR3671 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsIHC-Fr: Use at an assay dependent concentration; WB: 1:100000 - 1:500000; ICC: 1:100 - 1:250; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens keratin 13, type I (KRT13), transcript variant 2
Alternative NameCK13; K13; WSN2
Database LinkNP_002265
Entrez Gene 3860 Human
Entrez Gene 16663 Mouse
FunctionKeratins are a family of highly homologous proteins expressed as pairs of acidic and basic forms which make intermediate filaments in epithelial cells. Keratin 13 (CK13) is the major acidic keratin, which together with K4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia (1). White sponge nevus (WSN) is a rare autosomal dominant disorder of non-cornifying squamous epithelial differentiation that presents clinically as bilateral white, soft, thick plaques of the oral mucosa. In WSN, the restriction of lesions to mucosal epithelia and the suprabasal cell histopathology parallels the tissue-specific expression of keratins 4 and 13 in the differentiating cell layers (2).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Cytokeratin 13 antibody [EPR3671]; All lanes : Anti-Cytokeratin 13 antibody [EPR3671] at 1/100000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HACAT cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-Rabbit IgG at 1/2000 dilution.Predicted band size : 50 kDa.
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Other-Anti-Cytokeratin 13 antibody [EPR3671](TA307432); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cytokeratin 13 antibody [EPR3671]; TA307432 at 1/100 dilution staining Cytokeratin 13 in formalin-fixed, paraffin-embedded transitional cell usrinary bladder carcinoma tissue by immunohistochemistry. Detection: DAB staining.
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Immunohistochemistry (Frozen sections) - Anti-Cytokeratin 13 antibody [EPR3671]; TA307432 staining Cytokeratin 13 in Human vaginal epithelium tissue sections by Immunohistochemistry (IHC-Fr - frozen sections). Tissue was fixed with paraformaldehyde, permeabilized with 0.2% Triton in PBS and blocked with 1% fish skin gelatin for 30 minutes at 25°C. Samples were incubated with primary antibody (1/200) for 1 hour at 25°C. An Alexa Fluor?594-conjugated Goat anti-rabbit polyclonal (1/1000) was used as the secondary antibody.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 13 antibody [EPR3671](TA307432); TA307432 showing positive staining in Cervical carcinoma tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 13 antibody [EPR3671](TA307432); TA307432 showing positive staining in Normal tonsil squamous cells tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 13 antibody [EPR3671](TA307432); TA307432 showing negative staining in Glioma tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 13 antibody [EPR3671](TA307432); TA307432 showing negative staining in Breast carcinoma tissue.
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