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Anti-S100A9 Antibody EPR3556
Also for S100A9 (NM_002965)
|A synthetic peptide corresponding to residues near the C-terminus in human MRP14/S100-A9 was used as an immunogen.|
||Lot dependent; please refer to CoA along with shipment
||IHC: 1 : 100 - 250, WB: 1 : 1,000 - 10,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens S100 calcium binding protein A9 (S100A9)|
|60B8AG; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14|
|Myeloid-related protein (MRP14), or calcium-protecting protein (S100-A9), is a member of the S100 family proteins containing two EF-hand calcium-binding motifs (1). S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and they are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation (2). S100-A9 forms a heterodimer, calprotectin, with S100-A8 in a calcium-dependent manner (3). Calprotectin is a major calcium- and zinc-binding protein in the cytosol of neutrophils, monocytes, and keratinocytes (4). S100-A9 may function in the inhibition of casein kinase, and altered expression of this protein is associated with the disease cystic fibrosis (2).|
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Western blot - S100A9 antibody [EPR3556]; All lanes : Anti-S100A9 antibody [EPR3556] at 1/1000 dilution.Lane 1 : Human tonsil cell lysate.Lane 2 : Human peripheral blood leukocyte cell lysate .Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 13 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - S100A9 antibody [EPR3556]; TA307399, at a 1/100 dilution, staining S100A9 in paraffin embedded Human spleen tissue by Immunohistochemistry.