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Anti-S100A10 Antibody EPR3318


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Calpactin I Light Chain/S100A10 (clone EPR3318 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401038) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Calpactin I Light Chain/S100A10 was used as an immunogen.
Clone NameEPR3318 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:50; FC: 1:100; IHC-P: 1:100 - 1:250
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC.

Reference Data

Target NameHomo sapiens S100 calcium binding protein A10 (S100A10)
Alternative Name42C; ANX2L; ANX2LG; CAL1L; Ca[1]; CLP11; GP11; p10; P11
Database LinkNP_002957
Entrez Gene 6281 Human
FunctionS100 proteins are low-molecular-weight calcium-binding proteins of the EF-hand superfamily and appear to be involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation (1). Also, S100 proteins have been reported to localize to the plasma membrane in differentiated keratinocytes, suggesting a role in regulating calcium-dependent, membrane-associated events (3). The Calpactin I light chain (S100 calcium-binding protein A10; S100A10) is a member of the S100 family and it forms a heterotetrameric complex with another light chain, p11, and two heavy chains, annexin II and p36 (2). S100A10 is present in basal and spinous cells, in the cytoplasm, and is associated with the plasma membrane. S100A10, as well as a few other members of the S100 family, are suggested as transglutaminase substrates (3).
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-S100A10 antibody [EPR3318]; All lanes : Anti-S100A10 antibody [EPR3318] at 1/1000 dilution.Lane 1 : HACAT cell lysate.Lane 2 : HT29 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 11 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100A10 antibody [EPR3318]; Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue labelling S100A10 with TA307397 at 1/100 dilution.
Flow Cytometry - Anti-S100A10 antibody [EPR3318]; TA307397 staining S100A10 in the HT-29cell line by Flow Cytometry(red). Rabbit IgG was used as a negative control (green).


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