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Anti-TG Antibody EPR3615
|A synthetic peptide corresponding to residues near the C-term in human Thyroglobulin was used as an immunogen.|
||Lot dependent; please refer to CoA along with shipment
||WB: 1:500000 - 1:1e+006; IP: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens thyroglobulin (TG)|
Entrez Gene 7038 Human
|Thyroglobulin (TG) is a dimeric glycoprotein specific to the thyroid gland which belongs to the type-B carboxylesterase/lipase family. It is the precursor of the iodinated thyroid hormones triiodothyronine (T3) and thyroxine (T4) (1, 2). Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (2), and defective or impaired TG synthesis usually results in congenital goitrous hypothyroidism, virtual absence of TG in thyroid tissue, and the presence of an elevated concentration of iodoalbumin. The final result of these abnormalities is a decreased rate of T3 and T4 synthesis (3). |
|Druggable Genome Autoimmune thyroid disease|
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Western blot - Anti-Thyroglobulin antibody [EPR3615]; Anti-Thyroglobulin antibody [EPR3615] at 1/500000 dilution + Human thyroid lysate at 10 ug.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 305 kDa.