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Home Antibody All anti-TG antibodies

Anti-TG Antibody EPR3615

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307373
  • Rabbit monoclonal antibody against Thyroglobulin (clone EPR3615 )
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-term in human Thyroglobulin was used as an immunogen.
Clone NameEPR3615 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:500000 - 1:1e+006; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens thyroglobulin (TG)
Alternative NameAITD3; TGN
Database LinkNP_003226
FunctionThyroglobulin (TG) is a dimeric glycoprotein specific to the thyroid gland which belongs to the type-B carboxylesterase/lipase family. It is the precursor of the iodinated thyroid hormones triiodothyronine (T3) and thyroxine (T4) (1, 2). Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (2), and defective or impaired TG synthesis usually results in congenital goitrous hypothyroidism, virtual absence of TG in thyroid tissue, and the presence of an elevated concentration of iodoalbumin. The final result of these abnormalities is a decreased rate of T3 and T4 synthesis (3).
Related Pathway

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WB Image
Western blot - Anti-Thyroglobulin antibody [EPR3615]; Anti-Thyroglobulin antibody [EPR3615] at 1/500000 dilution + Human thyroid lysate at 10 µg.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 305 kDa.

 

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