OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TIMP1 antibodies

Anti-TIMP1 Antibody EPR1550

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307371
  • Rabbit monoclonal antibody against TIMP-1(clone EPR1550)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418808) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(2)
IHC(1)
spacer
Also for TIMP1 (NM_003254)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TIMP-1 was used as an immunogen.
Clone NameEPR1550 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens TIMP metallopeptidase inhibitor 1 (TIMP1)
Alternative NameCLGI; EPA; EPO; HCI; TIMP
Database LinkNP_003245
FunctionTissue inhibitor of metalloproteinase 1 (TIMP-1) is a stromal factor which forms complexes with various members of matrix metalloproteinases (MMPs) and irreversibly inactivates them. A multifunctional glycoprotein, TIMP-1 is one of the four members of TIMP family (TIMP 1-4) which exhibits 50% sequence similarity and expressed in wide variety of cells (1). TIMP-1 binds non-covalently in a 1:1 stoichiometric fashion to the active form of MMPs thereby inhibiting the proteolytic activity of these enzymes. In addition to inhibitory function, other studies have proposed growth protion, anti-apoptotic, anti- and pro-angiogenic functions for TIMP-1. TIMP-1 expression has been observed in poor clinical outcome in many cancer types, making it ideal prognostic marker in various cancer (2).
Related Pathway
Hemostasis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TIMP1 antibody [EPR1550]; All lanes : Anti-TIMP1 antibody [EPR1550] at 1/1000 dilution.Lane 1 : HL60+TPA cell lysates.Lane 2 : PBMC cell lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 23 kDa.
WB Image
Western blot - TIMP1 antibody [EPR1550]; Anti-TIMP1 antibody [EPR1550] at 1/1000 dilution + TIMP1 recombinant protein at 10 µg.Predicted band size : 23 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TIMP1 antibody [EPR1550]; TA307371, at 1/250 dilution staining TIMP1 in paraffin-embedded Human liver tissue, by Immunohistochemistry.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title