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Anti-TNFRSF10D Antibody EPR3588(2)
Also for TNFRSF10D (NM_003840)
|A synthetic peptide corresponding to residues in human DcR2 was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D)|
|CD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD|
Entrez Gene 8793 Human
|DcR2, a 386-amino acid protein, is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis (1). DcR2 is widely expressed in particular in fetal kidney, lung and liver, and in adult testis and liver (2).|
|TransmembraneDruggable Genome Cytokine-cytokine receptor interactionApoptosisNatural killer cell mediated cytotoxicity|
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Western blot - DcR2 antibody [EPR3588(2)]; All lanes : Anti-DcR2 antibody [EPR3588(2)] at 1/1000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : Fetal kidney lysate.Lane 3 : Human prostate lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 36 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DcR2 antibody [EPR3588(2)]; TA307338, at 1/250 dilution, staining DcR2 in paraffin-embedded Human kidney tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DcR2 antibody [EPR3588(2)]; TA307338, at 1/250 dilution, staining DcR2 in paraffin-embedded Human tonsil tissue by Immunohistochemistry.