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Home Antibody All anti-TNFRSF10D antibodies

Anti-TNFRSF10D Antibody EPR3588(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307338
  • Rabbit monoclonal antibody against DcR2(clone EPR3588(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401258) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for TNFRSF10D (NM_003840)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DcR2 was used as an immunogen.
Clone NameEPR3588(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D)
Alternative NameCD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD
Database LinkNP_003831
Entrez Gene 8793 Human
FunctionDcR2, a 386-amino acid protein, is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis (1). DcR2 is widely expressed in particular in fetal kidney, lung and liver, and in adult testis and liver (2).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionApoptosisNatural killer cell mediated cytotoxicity

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - DcR2 antibody [EPR3588(2)]; All lanes : Anti-DcR2 antibody [EPR3588(2)] at 1/1000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : Fetal kidney lysate.Lane 3 : Human prostate lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 36 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DcR2 antibody [EPR3588(2)]; TA307338, at 1/250 dilution, staining DcR2 in paraffin-embedded Human kidney tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DcR2 antibody [EPR3588(2)]; TA307338, at 1/250 dilution, staining DcR2 in paraffin-embedded Human tonsil tissue by Immunohistochemistry.

 

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