OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-BCL10 antibodies

Anti-BCL10 Antibody EPR3175


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Bcl-10(clone EPR3175)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418351) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human EN1 was used as an immunogen.
Clone NameEPR3175 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 10 (BCL10)
Alternative Namec-E10; CARMEN; CIPER; CLAP; IMD37; mE10
Database LinkNP_003912
Entrez Gene 8915 Human
FunctionBcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1, 2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor-mediated lymphocyte proliferation and signaling to NF-B, which controls the expression of genes critical for cell survival, proliferation, and immune responses (3,4). Defects in Bcl-10 have been identified in various types of cancer.
Related PathwayDruggable Genome T cell receptor signaling pathwayB cell receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Bcl10 antibody [EPR3175]; All lanes : Anti-Bcl10 antibody [EPR3175] at 1/1000 dilution.Lane 1 : Daudi cell lysate.Lane 2 : Raji cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : HuT-78 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 26 kDa.
Immunocytochemistry/ Immunofluorescence - Bcl10 antibody [EPR3175]; TA307332, at 1/100 dilution, staining Bcl10 in HeLa cells by Immunofluorescence.


Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title