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Anti-BCL10 Antibody EPR3175
Also for BCL10 (NM_003921)
|A synthetic peptide corresponding to residues in human EN1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||ICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt or IHC-P.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens B-cell CLL/lymphoma 10 (BCL10)|
|c-E10; CARMEN; CIPER; CLAP; mE10|
|Bcl-10 is an adaptor protein with a caspase recruitment domain (CARD) that promotes apoptosis and activates pro-caspase 9 and NF-kB (1, 2). Bcl-10 also interacts with other CARD domain containing proteins including CARD9, 10, 11 and 14. Bcl-10 is found to form a complex with MALT1, a protein known to be translocated in MALT lymphomas. Bcl-10 and MALT1 play a critical role in antigen receptor-mediated lymphocyte proliferation and signaling to NF-B, which controls the expression of genes critical for cell survival, proliferation, and immune responses (3,4). Defects in Bcl-10 have been identified in various types of cancer.|
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Western blot - Bcl10 antibody [EPR3175]; All lanes : Anti-Bcl10 antibody [EPR3175] at 1/1000 dilution.Lane 1 : Daudi cell lysate.Lane 2 : Raji cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : HuT-78 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 26 kDa.
Immunocytochemistry/ Immunofluorescence - Bcl10 antibody [EPR3175]; ab108328, at 1/100 dilution, staining Bcl10 in HeLa cells by Immunofluorescence.