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Home Antibody All anti-UCHL1 antibodies

Anti-UCHL1 Antibody EPR4118

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SKU Description Amount Price Availability*  
TA307323
  • Rabbit monoclonal antibody against PGP9.5(clone EPR4118)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401345) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for UCHL1 (NM_004181)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PGP9.5 was used as an immunogen.
Clone NameEPR4118 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC/IF: Use at an assay dependent concentration; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; FC: 1:10 - 1:100
Predicted MW Explanation 24 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC.

Reference Data

Target NameHomo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)
Alternative NameHEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1
Database LinkNP_004172
Entrez Gene 7345 Human
Entrez Gene 22223 Mouse
Entrez Gene 29545 Rat
FunctionPGP9.5 belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. It is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in PGP9.5 may be associated with Parkinson disease and Alzheimer’s disease.
Related PathwayProteaseDruggable Genome Parkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - PGP9.5 antibody [EPR4118]; All lanes : Anti-PGP9.5 antibody [EPR4118] at 1/1000 dilution.Lane 1 : Fetal brain cell lysate.Lane 2 : Y79 cell lysate.Lane 3 : U87-MG cell lysate.Lane 4 : SH-SY5Y cell lysate.Lane 5 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 24 kDa.Observed band size : 25 kDa .
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PGP9.5 antibody [EPR4118]; Immunohistochemical staining of PGP9.5 in paraffin embedded Human glioma tissue, using TA307323 at a 1/250 dilution.
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