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Anti-TGM2 Antibody EP2957


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307277 Rabbit monoclonal antibody against Transglutaminase 2(clone EP2957) 100ul $325 In Stock
LC401458 TGM2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Transglutaminase 2 was used as an immunogen.
Clone NameEP2957 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens transglutaminase 2 (TGM2), transcript variant 1
Alternative NameG-ALPHA-h; GNAH; HEL-S-45; TG2; TGC
Database LinkNP_004604
Entrez Gene 7052 Human
Entrez Gene 21817 Mouse
FunctionTransglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Transglutaminase 2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, this protein is an autoantigen implicated in celiac disease.
Related PathwayDruggable Genome Huntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Transglutaminase 2 antibody [EP2957]; All lanes : Anti-Transglutaminase 2 antibody [EP2957] at 1/10000 dilution.Lane 1 : U87-MG cell lysate.Lane 2 : A549 cell lysate.Lane 3 : HUVEC cell lysate .Lysates/proteins at 10 ug per lane.Predicted band size : 77 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Transglutaminase 2 antibody [EP2957]; TA307277, at 1/100 dilution, staining Transglutaminase 2 in paraffin-embedded Human kidney tissue by Immunohistochemistry.


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