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Home Antibody All anti-CDK2AP1 antibodies

Anti-CDK2AP1 Antibody Clone-R76

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307276
  • Rabbit monoclonal antibody against CDK2AP1(clone Clone-R76)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401472) , 20ug Explanation
100ul 325 In Stock
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WB(1)
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Also for CDK2AP1 (NM_004642)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CDK2AP1 was used as an immunogen.
Clone NameClone-R76 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), transcript variant 1
Alternative Namedoc-1; DOC1; DORC1; p12DOC-1; ST19
Database LinkNP_004633
Entrez Gene 8099 Human
Entrez Gene 13445 Mouse
FunctionCyclin-dependent kinase 2-associated protein 1 (CDK2AP1), also known as DOC-1, is a tumor suppressor in the CDK2AP family (1). CDK2AP1 is expressed in all normal human tissues, and it is an inhibitor of G(1)/S transition through the down-regulation of CDK2 (1, 2). As an essential gene for early embryonic development, CDK2AP1 also associates with DNA polymerase α/primase and mediates the phosphorylation of the large p180 catalytic subunit, suggesting that it may be a potential regulator of DNA replication in the S phase of the cell cycle (1, 2). It is a core subunit of MBD2/NuRD and MBD3/NuRD, which is involved in DNA methylation (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CDKA1 / DOC1 antibody [Clone-R76]; All lanes : Anti-CDKA1 / DOC1 antibody [Clone-R76] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : LNCaP cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 12 kDa.

 

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