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Anti-CDK2AP1 Antibody Clone-R76
Also for CDK2AP1 (NM_004642)
|A synthetic peptide corresponding to residues in human CDK2AP1 was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|Does not react with Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens cyclin-dependent kinase 2 associated protein 1 (CDK2AP1), transcript variant 1|
|doc-1; DOC1; DORC1; p12DOC-1; ST19|
|Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1), also known as DOC-1, is a tumor suppressor in the CDK2AP family (1). CDK2AP1 is expressed in all normal human tissues, and it is an inhibitor of G(1)/S transition through the down-regulation of CDK2 (1, 2). As an essential gene for early embryonic development, CDK2AP1 also associates with DNA polymerase α/primase and mediates the phosphorylation of the large p180 catalytic subunit, suggesting that it may be a potential regulator of DNA replication in the S phase of the cell cycle (1, 2). It is a core subunit of MBD2/NuRD and MBD3/NuRD, which is involved in DNA methylation (3).|
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Western blot - CDKA1 / DOC1 antibody [Clone-R76]; All lanes : Anti-CDKA1 / DOC1 antibody [Clone-R76] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HUVEC cell lysate.Lane 4 : LNCaP cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 12 kDa.