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 Home All anti-BAG4 antibodies

Anti-BAG4 Antibody EPR3597

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SKU Description Amount Price Availability*  
TA307269
  • Rabbit monoclonal antibody against SODD(clone EPR3597)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417692) , 20ug
 100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)
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Also for BAG4 (NM_004874)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SODD was used as an immunogen.
Clone NameEPR3597 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, WB: 1:1,000 - 10,000,
BufferStore at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens BCL2-associated athanogene 4 (BAG4), transcript variant 1
Alternative NameBAG-4; SODD
Database LinkNP_004865
FunctionSODD (BAG4) is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. SODD was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost (1).
Related Pathway

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WB Image
Western blot analysis on (A) HeLa and (B) Molt-4 cell lysates using anti-SODD RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human colonic adenocarcinoma tissue using anti-SODD RabMAb .

 

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