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Home Antibody All anti-BAG4 antibodies

Anti-BAG4 Antibody EPR3596


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307268 Rabbit monoclonal antibody against SODD(clone EPR3596) 100ul $325 3-7 Days
LC417692 BAG4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SODD was used as an immunogen.
Clone NameEPR3596 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application * Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens BCL2 associated athanogene 4 (BAG4), transcript variant 1
Alternative NameBAG-4; SODD
Database LinkNP_004865
Entrez Gene 9530 Human
FunctionSODD (Silencer of Death Domain) is a member of the SODD-related protein family. SODD is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. SODD was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells, which undergo apoptosis when integrin mediated matrix contacts are lost.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


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