OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BAG4 antibodies

Anti-BAG4 Antibody EPR3596

div

Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307268 Rabbit monoclonal antibody against SODD(clone EPR3596) 100ul $325 3-7 Days
LC417692 BAG4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
Add to Shopping Cart
spacer
WB(1)
IF(1)
Write Review & Get Rewarded
X

Write a review and get rewarded!

Review this antibody and earn an OriGene coupon or Amazon giftcard

Follow these easy steps to reward yourself:

  1. Sign in to your account, or register for a new account;
  2. Write a review;
  3. Receive a coupon or giftcard once your review is accepted.

Click the button to start writing a review


OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SODD was used as an immunogen.
Clone NameEPR3596 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens BCL2 associated athanogene 4 (BAG4), transcript variant 1
Alternative NameBAG-4; SODD
Database LinkNP_004865
Entrez Gene 9530 Human
FunctionSODD (Silencer of Death Domain) is a member of the SODD-related protein family. SODD is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. SODD was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells, which undergo apoptosis when integrin mediated matrix contacts are lost.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot - Silencer of Death Domain antibody [EPR3596]; All lanes : Anti-Silencer of Death Domain antibody [EPR3596] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : Molt-4 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 50 kDa.Observed band size : 65 kDa .
spacer

IF Image
Immunocytochemistry/ Immunofluorescence - Silencer of Death Domain antibody [EPR3596]; Immunofluorescent staining of Silencer of Death Domain in HeLa cells, using TA307268 at a 1/100 dilution.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge