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Home Antibody All anti-ISG15 antibodies

Anti-ISG15 Antibody EPR3445

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307250 Rabbit monoclonal antibody against ISG15 (clone EPR3445 ) 100ul $325 In Stock
LC417516 ISG15 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for ISG15 (NM_005101)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ISG15 was used as an immunogen.
Clone NameEPR3445 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, WB: 1:2000 - 5000,
Predicted MW Explanation 15 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens ISG15 ubiquitin-like modifier (ISG15)
Alternative NameG1P2; hUCRP; IFI15; IMD38; IP17; UCRP
Database LinkNP_005092
Entrez Gene 9636 Human
FunctionISG15 is a ubiquitin like protein that is covalently conjugated to cellular proteins after IFN-alpha/beta stimulation (2). ISG15 is conjugated to their targets by an enzymatic cascade involving an E1 activating enzyme, an E2 conjugating enzyme, and in some cases an E3 ligase. ISG15 conjugation plays an important role by impacting nuclear and cytoplasmic functions as well as in antiviral response because a human virus, influenza B virus, inhibits ISG15 conjugation. However, the biological function of ISG15 modification remains unknown, largely because only a few human ISG15 target proteins have been identified (3).
Related PathwaySecreted ProteinDruggable Genome RIG-I-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - ISG15 antibody [EPR3445]; All lanes : Anti-ISG15 antibody [EPR3445] at 1/2000 dilution.Lane 1 : Hela cell lysate treated with IFN α.Lane 2 : Daudi cell lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 15 kDa.Observed band size : 15 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ISG15 antibody [EPR3445]; Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, staining ISG15 with TA307250 at 1/100 dilution.
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