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Home Antibody All anti-EWSR1 antibodies

Anti-EWSR1 Antibody EPR4647

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307236
  • Rabbit monoclonal antibody against EWSR1 / EWS(clone EPR4647)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401610) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(2)
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Also for EWSR1 (NM_005243)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human EWSR1/EWS was used as an immunogen.
Clone NameEPR4647 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000
Predicted MW Explanation 68 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 2
Alternative NamebK984G1.4; EWS
Database LinkNP_005234
Entrez Gene 2130 Human
Entrez Gene 14030 Mouse
Entrez Gene 289752 Rat
FunctionEWSR1 / EWS is a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this protein and various proteins that are transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in EWSR1 / EWS are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors (1).
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-EWSR1 antibody [EPR4647]; All lanes : Anti-EWSR1 antibody [EPR4647] at 1/10000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : F9 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 68 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EWSR1 antibody [EPR4647]; Immunohistochemical analysis of paraffin-embedded Human colon tissue labelling EWSR1 with TA307236 at 1/250 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EWSR1 antibody [EPR4647]; Immunohistochemical analysis of paraffin-embedded Human colonic adenocarcinoma tissue labelling EWSR1 with TA307236 at 1/250 dilution.
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