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Home Antibody All anti-FBLN5 antibodies

Anti-FBLN5 Antibody EPR685

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307164 Rabbit monoclonal antibody against Fibulin-5(clone EPR685) 100ul $325 In Stock
LC401904 FBLN5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for FBLN5 (NM_006329)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Fibulin-5 was used as an immunogen.
Clone NameEPR685 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferPreservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens fibulin 5 (FBLN5)
Alternative NameADCL2; ARCL1A; ARMD3; DANCE; EVEC; FIBL-5; UP50
Database LinkNP_006320
Entrez Gene 10516 Human
FunctionFibulin-5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries, but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, Fibulin-5 may play a role in vascular development and remodeling. Defects in Fibulin-5 are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3) (1).
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Fibulin 5 antibody [EPR685]; All lanes : Anti-Fibulin 5 antibody [EPR685] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 50 kDa.
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