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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-BACE1 antibodies

Anti-BACE1 Antibody EPR3956

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA307125
  • Rabbit monoclonal antibody against BACE1(clone EPR3956)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402147) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
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Also for BACE1 (NM_012104)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a
Synonyms:ASP2; BACE; HSPC104
ImmunogenA synthetic peptide corresponding to residues in human BACE1 was used as an immunogen.
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Store at -20C.
Clone NameEPR3956 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsIP: 1:10 - 100, WB: 1:1,000 - 10,000,
BackgroundCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE1. BACE1 is a member of the peptidase A1 protein family, a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on (A) fetal brain, (B) SH-SY5Y, (C) mouse brain and (D) rat brain lysates using anti-BACE1 RabMAb .

 

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