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Anti-EVL Antibody EPR4561
|A synthetic peptide corresponding to residues in human EVL was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; ICC: 1:500 - 1:1000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens Enah/Vasp-like (EVL)|
Entrez Gene 51466 Human
Entrez Gene 14026 Mouse
Entrez Gene 79115 Rat
|EVL is an Ena/VASP-like protein that is involved in a range of processes dependent on cytoskeleton remodeling and cell polarity, such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Furthermore, it is required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes. EVL is targeted to the leading edge of lamellipodia and the distal tip of stress fibers by interacting with a number of proteins. In activated T-cells, it localizes to the F-actin collar and the distal tip of microspikes (1).|
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Western blot - Enah/Vasp-like antibody [EPR4561]; All lanes : Anti-Enah/Vasp-like antibody [EPR4561] at 1/10000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 45 kDa.