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Anti-EVL Antibody EPR4561


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against EVL(clone EPR4561)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414045) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human EVL was used as an immunogen.
Clone NameEPR4561 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000; ICC: 1:500 - 1:1000
Predicted MW Explanation 45 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens Enah/Vasp-like (EVL)
Alternative NameRNB6
Database LinkNP_057421
Entrez Gene 51466 Human
Entrez Gene 14026 Mouse
Entrez Gene 79115 Rat
FunctionEVL is an Ena/VASP-like protein that is involved in a range of processes dependent on cytoskeleton remodeling and cell polarity, such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Furthermore, it is required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes. EVL is targeted to the leading edge of lamellipodia and the distal tip of stress fibers by interacting with a number of proteins. In activated T-cells, it localizes to the F-actin collar and the distal tip of microspikes (1).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Enah/Vasp-like antibody [EPR4561]; All lanes : Anti-Enah/Vasp-like antibody [EPR4561] at 1/10000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 45 kDa.


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