OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-APBB1IP antibodies

Anti-APBB1IP Antibody EP2806

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307075
  • Rabbit monoclonal antibody against RIAM (clone EP2806 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC412750) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
spacer
Also for APBB1IP (NM_019043)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human RIAM was used as an immunogen.
Clone NameEP2806 IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:50, WB: 1:2000 - 10,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein (APBB1IP)
Alternative NameINAG1; PREL1; RARP1; RIAM
Database LinkNP_061916
FunctionRIAM (a Rap1-GTP-interacting adapter molecule) defines a family of adaptor molecules that contain a RA-like (Ras association) domain, a PH (pleckstrin homology) domain, and various proline-rich motifs (1). RIAM directly binds to Ena/VASP proteins, important modulators of cell migration that localize to focal adhesions and stress fibers, and co-localizes with them at focal adhesions in response to Ras activation. Moreover, RIAM directly binds to activated Ras in a phosphoinositide-dependent manner. RIAM is believed to be the first direct link between Ras signalling and cytoskeletal remodelling via Ena/VASP proteins during cell migration and spreading (2).
Related Pathway
Hemostasis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - RIAM antibody [EP2806]; All lanes : Anti-RIAM antibody [EP2806] at 1/2000 dilution.Lane 1 : Human Lymph node lysate.Lane 2 : Fetal brain lysate.Lane 3 : Human spleen lysate.Lane 4 : Jurkat cell lysate.Lane 5 : HL-60 + retinoic acid cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 73 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RIAM antibody [EP2806]; TA307075, at 1/100 dilution, staining RIAM in paraffin-embedded Human tonsil tissue by Immunohistochemistry.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title