OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-NEUROG2 antibodies

Anti-NEUROG2 Antibody EPR4177

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307052
  • Rabbit monoclonal antibody against Neurogenin-2(clone EPR4177)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411396) , 20ug
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IF(1)
spacer
Also for NEUROG2 (NM_024019)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Neurogenin-2 was used as an immunogen.
Clone NameEPR4177 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens neurogenin 2 (NEUROG2)
Alternative NameAtoh4; bHLHa8; Math4A; ngn-2; NGN2
Database LinkNP_076924
FunctionNeurogenin-2 (Ngn-2) is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factors that play an important role in neurogenesis from migratory neural crest cells (1). In particular, it is critical for the differentiation and survival of midbrain dopaminergic neurons (2). Neurogenin-2, in collaboration with extrinsic signal retinoic acid (RA), triggers transcriptionally active chromatin in spinal motor neurons during development (3). Neurogenin-2 is bound by Retinoic acid receptor (RAR), and RAR is thereby recruited to motor neuron genes targeted by Neurogenin-2 (3). RA then facilitates the recruitment of a histone acetyltransferase CBP to the Neurogenin-2/RAR-complex, markedly inducing histone H3/H4-acetylation (3).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Neurogenin 2 antibody [EPR4177]; All lanes : Anti-Neurogenin 2 antibody [EPR4177] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 29 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - Neurogenin 2 antibody [EPR4177]; Immunofluorescent staining of Neurogenin 2 in SH-SY-5Y cells using TA307052 at 1/100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title