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Anti-KCNH1 Antibody EPR3802
Also for KCNH1 (NM_172362)
|A synthetic peptide corresponding to residues in human KCNH1 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 1 (KCNH1), transcript variant 1|
|EAG; EAG1; h-eag; Kv10.1|
|Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH1 is a member of the potassium channel, voltage-gated, subfamily H. It is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. KCNH1 is highly expressed in brain and in myoblasts. Overexpression may confer a growth advantage to cancer cells and favor tumor cell proliferation (1).|
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Western blot - KCNH1 antibody [EPR3802]; All lanes : Anti-KCNH1 antibody [EPR3802] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : A673 cell lysate .Lysates/proteins at 10 µg per lane.Predicted band size : 111 kDa.