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Anti-DNMT3A Antibody EPR2408
Also for DNMT3A (NM_175629)
|A synthetic peptide corresponding to residues in human Dnmt3a was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), transcript variant 1|
|DNMT3A2; M.HsaIIIA; TBRS|
Entrez Gene 1788 Human
|CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus; its expression is developmentally regulated.|
|Druggable Genome Cysteine and methionine metabolismMetabolic pathways|
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Western blot - Anti-Dnmt3a antibody [EPR2408]; All lanes : Anti-Dnmt3a antibody [EPR2408] at 1/1000 dilution.Lane 1 : SH SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 102 kDa.