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Anti-DNMT3A Antibody EPR2408
Also for DNMT3A (NM_175629)
|A synthetic peptide corresponding to residues in human Dnmt3a was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF or IHC-P.|
|Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), transcript variant 1|
|CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus; its expression is developmentally regulated.|
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Western blot - Anti-Dnmt3a antibody [EPR2408]; All lanes : Anti-Dnmt3a antibody [EPR2408] at 1/1000 dilution.Lane 1 : SH SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 102 kDa.