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Anti-NCAM1 Antibody EPR2566
Also for NCAM1 (NM_181351)
|A synthetic peptide corresponding to residues in extracellular domain of human CD56/NCAM was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens neural cell adhesion molecule 1 (NCAM1), transcript variant 2|
|CD56; MSK39; NCAM|
Entrez Gene 4684 Human
|The neural cell adhesion molecule (NCAM/CD56) is a homophilic binding glycoprotein belonging to immunoglobulin (Ig) superfamily. It is commonly found on the surface of neurons, NK cells, gilas, and neuroendocrine tissues, and it is involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM mediates axon growth, fasciculation, and cell adhesion by homophilic and heterophilic interactions (1). Due to alternative splicing, at least 27 different isoforms of NCAM mRNAs has been identified, leading to variety of NCAM isoforms (2). Three major NCAM isoforms are: 140 and 180 kDa transmembrane forms (NCAM-140, NCAM-180), and 120 kDa glycophosphatidylinositol (GPI)-linked isoform (NCAM120) (3).|
|ES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Prion diseases|
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Western blot - Anti-NCAM antibody [EPR2566]; All lanes : Anti-NCAM antibody [EPR2566] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : Human fetal brain cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 95 kDa.Observed band size : 140-180 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NCAM antibody [EPR2566]; Immunohistochemical analysis of Formalin-fixed, paraffin-embedded Human glioma tissue staining NCAM with TA306984 at 1/100 dilution.