Home Antibody All anti-LRRC19 antibodies
Also for LRRC19 (NM_022901)
|LRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.|
||WB: 1 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens leucine rich repeat containing 19 (LRRC19)|
Entrez Gene 64922 Human
Entrez Gene 100061 Mouse
|LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.|
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Western blot analysis of LRRC19 in K562 cell lysate with LRRC19 antibody at 1 ug/mL.
Immunocytochemistry of LRCC19 in K562 cells with LRCC19 antibody at 2.5 ug/mL.