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Home Antibody All anti-LRRC19 antibodies

Anti-LRRC19 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306940
  • Rabbit Polyclonal LRRC19 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenLRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens leucine rich repeat containing 19 (LRRC19)
Alternative NameFLJ21302
Database LinkNP_075052
Entrez Gene 64922 Human
Entrez Gene 100061 Mouse
FunctionLRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LRRC19 in K562 cell lysate with LRRC19 antibody at 1 ug/mL.
IF Image
Immunocytochemistry of LRCC19 in K562 cells with LRCC19 antibody at 2.5 ug/mL.

 

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