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Anti-OCLN Antibody


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SKU Description Amount Price Availability*  
  • Rabbit Polyclonal OCLN Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419249) , 20ug Explanation
100ug $325 In Stock
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OriGene Data

ImmunogenOCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens occludin (OCLN), transcript variant 1
Alternative NameBLCPMG; PPP1R115
Database LinkNP_002529
Entrez Gene 100506658 Human
Entrez Gene 18260 Mouse
Entrez Gene 83497 Rat
FunctionTight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.
Related Pathway

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WB Image
Western blot analysis of OCLN in human liver tissue lysate with OCLN antibody at 1 ug/ml.
IHC Image
Immunohistochemistry of OCLN in human liver tissue with OCLN antibody at 2.5 ug/ml.


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