Home Antibody All anti-FTO antibodies
Also for FTO (NM_001080432)
|FTO antibody was raised against a 15 amino acid peptide from near the amino terminus of human FTO.|
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens fat mass and obesity associated (FTO)|
Entrez Gene 79068 Human
|Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.|
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Western blot analysis of FTO in human uterus tissue lysate with FTO antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry of FTO in mouse brain tissue with FTO antibody at 2.5 ug/ml.