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Home Antibody All anti-ATOH8 antibodies

Anti-ATOH8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306753
  • Rabbit Polyclonal ATOH8 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409915) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenATOH8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ATOH8.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens atonal homolog 8 (Drosophila) (ATOH8)
Alternative NamebHLHa21; HATH6
Database LinkNP_116216
FunctionBasic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43–57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.
Related Pathway

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WB Image
Western blot analysis of ATOH8 in A-20 cell lysate with ATOH8 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of ATOH8 in mouse brain tissue with ATOH8 antibody at 5 ug/ml.

 

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